Solutions · Pharma & Life Sciences

Rich, live context for pharma AI, from any kind of data.

A safety narrative, a lesion image, a claims record, and a paper published this morning each carry meaning your AI needs: what it says, where it came from, who may use it, and how current it is. Nextdata OS keeps that context attached and up to date across every format, so agents can take on work that schema-first stacks can’t support.

The problem

Most of what matters in pharma never fits a table.

 

Conventional stacks are schema-first: everything has to be modeled into rows and columns before anything can use it. That works for claims and sales. It fails for the protocol, the case narrative, the image, and the new paper, which is where most of the signal lives. And what does make it through arrives stripped of its meaning, its source, and its permissions, usually a day or more behind.

Lost on the way in

What a field or finding actually means
Where it came from, and which version
Who may use it, and for what
How it relates to other records
How current it is

Left out entirely

Literature and preprints
Protocols and clinical notes
Safety narratives and case reports
Medical images and annotations
MSL and field notes

Why it’s hard

You can’t bolt context back on afterward.

 

Teams try. A catalog describes the tables, a vector store holds the documents, a semantic model sits behind each dashboard, and nightly jobs refresh it all. Each piece holds a fragment of the context. None of them enforce it, and none are current when an agent asks. So the model reasons over a stale, partial picture, gives different answers to different people, and can’t show its sources. In pharma, that’s where AI stalls: not at the model, but at what the model gets to see.

Teams try.

01

A catalog describes the tables

02

A vector store holds the documents

03

A semantic model sits behind each dashboard

04

Nightly jobs refresh it all

Each piece holds a fragment of the context. None of them enforce it, and none are current when an agent asks.

The solution

Context that stays attached, in any format, as it changes.

 

Nextdata OS turns every source (tables, documents, images, and feeds) into autonomous data products. Each one keeps its context with it: definitions, provenance, permitted-use policy, relationships to other products, and freshness. Products update as their sources change, and agents reach them through standard interfaces, including MCP. Nothing has to be forced into a schema first, and nothing leaves the systems you already run.

01 / Any source, any format

Tables & records

Claims & EHR patient journeys
Registries & outcomes
Assay & biomarker data
CRM & field activity

Snowflake · Databricks · Azure · AWS

Documents, images & feeds

Literature & preprints
Protocols & clinical notes
Safety narratives & case reports
Medical images
MSL & field notes

No schema required up front.

02 / Nextdata OS

Context-rich data products

Meaning & definitions
Provenance & relationships
Permitted-use policy & freshness

Updated as sources change. Linked across formats.

Live context layer

What · Where from · Who may · How fresh

Attached to the data, not rebuilt downstream. Current at the moment an agent asks.

03 / Every consumer

Agents, models & analysts

Reason across every format
Answers show their sources
Policy checked on every use

Shared use cases

Safety signals
Patient finding
Trial design & cohorts
Responder analysis

FIG. 1 — Every source keeps its context (meaning, provenance, permissions, freshness) and serves it live to any agent, model, or analyst.

01 · Any source

Tables & records

  • Claims & EHR patient journeys
  • Registries & outcomes
  • Assay & biomarker data
  • CRM & field activity

Documents, images & feeds

  • Literature & preprints
  • Protocols & clinical notes
  • Safety narratives & case reports
  • Medical images
  • MSL & field notes

02 · Nextdata OS

 

Context-rich data products

Clinical

 

Safety

 

Commercial

 
      
 Structured
 Unstructured
Linked across formats

STRUCTURED · UNSTRUCTURED · LINKED ACROSS FORMATS

Live context layer

Meaning &definitions
Meaning & definitions
Provenance &relationships
Provenance & relationships
Permitted-use policy & freshness
Permitted-use policy & freshness

Attached to the data, not rebuilt downstream. Current at the moment an agent asks.

03 · Every consumer

Agents, models & analysts

Answers show their sources

 Safety signals

 Patient finding

 Trial design & cohorts

 Responder analysis

How it works

01

Any format, no schema first

Tables, documents, images, and feeds are usable as they are. Nothing has to be modeled into rows before AI can reason over it.

02

Context that stays attached

Meaning, provenance, and relationships travel with the data, so an agent knows what a record says and where it came from.

03

Current when it’s asked

Products update as their sources change, so an agent reasons over this morning’s case reports, not last week’s extract.

04

Governed at every use

Permitted-use policy is checked each time a person or agent uses the data, and every answer traces back to its sources.

What it unlocks

Use cases schema-first stacks can’t deliver.

 

Each depends on context from more than one format, and most depend on it being current.

Safety signals

Signals show up in narratives, literature, and case reports before structured fields catch up. Agents assemble and rank them continuously, with every source traceable for reviewers.

Patient finding

Delayed diagnosis shows up across claims, referrals, and clinical notes together. Find the pattern with permitted-use policy checked on every query.

Trial design & cohort exploration

Test inclusion criteria against patient data and the latest literature in one pass, instead of waiting on a bespoke extract.

Responder analysis

Link biomarkers, images, and outcomes at the patient level to see who responds, including the evidence that never fit a table.

Why now, why you

Top-10 ambition, without a top-10 platform team.

 

Mid-size and emerging pharma carry the same AI mandate as the majors, without the headcount to model every source into a warehouse first. Nextdata adds the context layer on top of the clouds, warehouses, and lakehouses you already run, so the documents and images you couldn’t use before become usable, without a migration.

01Works on Snowflake, Databricks, Azure, and AWS
02No migration, no schema rework
03Unstructured sources usable without a modeling project

Proof

Built by the team behind data mesh. Proven in pharma.

 

Nextdata was founded by Zhamak Dehghani, who created data mesh. At a commercial-stage immunology biotech, Nextdata connected unstructured scientific literature with structured patient data for trial design, gave analysts and agents the same answer to the same question, and took four AI use cases from stalled to live in under a year. The work is now expanding from commercial and clinical research to finance, tech ops, and supply chain.

Zhamak Dehghani

Zhamak Dehghani

Founder and CEO

Cornelius Willis

Cornelius Willis

Head of Marketing

Jörg Schad

Jörg Schad

Head of Engineering

Sina Jahan

Sina Jahan

Head of Product Engineering

Nextdata teamNextdata teamNextdata teamNextdata team

Select customers

mars
pepsi
westpac
argenx

Customer Perspective

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Customer Name

Title, Pharma Company

Next step

Bring one AI use case that’s short on context.

 

In 20 minutes we’ll map which sources it needs, what context they lose today, and what it would take to give your agents the full picture.

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